Over 30 years ago, Claire Forrester survived the terrible car accident that killed her husband and sent her into early labor. Now her daughter, Paige, is a successful oncologist battling her own medical condition, one that requires life-saving surgery. At the hospital where she works, Paige meets Gwen St. James, an accomplished make-up artist whose own past is filled with questions. Raised in a convent, Gwen never knew the identity of her parents. Soon the ties of friendship between Paige and Gwen grow into something stronger, something more like the ties between sisters.